Hypericum perforatum L. as Adjuvant to Opioid Analgesia in an Animal Model of Migraine

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Hypericum perforatum L. as Adjuvant to Opioid Analgesia in an Animal Model of Migraine

Aims: Despite their high analgesic efficacy, opioids can provide only partial pain relief during a migraine attack and their tolerability profile is unsatisfactory. The aim of the present study was to investigate the potentiating properties of Hypericum perforatum L. (SJW) to identify a safe and tolerable adjuvant to opioid analgesia in migraine therapy. Study Design: Experimental study. Place ...

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The Biological Activities of Hypericum Perforatum L.

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Essential oil composition of Hypericum perforatum L. and Hypericum scabrum L. growing wild in Tajikistan

The essential oils obtained by hydrodistillation from the aerial parts of Hypericum perforatum L. and Hypericum scabrum L. from plants growing wild in Tajikistan were analyzed by GC-MS. Sixty-six compounds were identified in the essential oils of H. perforatum with germacrene D (13.7%), α-pinene (5.1%), (E)-caryophyllene (4.7%), n-dodecanol (4.5%), caryophyllene oxide (4.2%), bicyclogermacrene ...

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Antioxidant activity relationship of phenolic compounds in Hypericum perforatum L.

BACKGROUND The St John's Wort (Hypericum perforatum; Clusiaceae) has been used in traditional and modern medicine for a long time due to its high content of biologically active phenolics. The purpose of this work was to develop a method for their fractionation and identification, and to determine the most active antioxidant compounds in plant extract. RESULTS An LC-MS method which enables fas...

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A review of the antibacterial activity of Hypericum perforatum L.

Hypericum perforatum L. (Hypericaceae) is a perennial herb that is commonly known as St. John's Wort. The plant has been valued for its important biological and chemical perspectives and its use in the treatment of infectious diseases has been documented in ethnobotanical reports. Most recent interest in H. perforatum has focused on its antidepressant effects, and only recently has its antimicr...

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ژورنال

عنوان ژورنال: British Journal of Medicine and Medical Research

سال: 2014

ISSN: 2231-0614

DOI: 10.9734/bjmmr/2014/7138